Nucleosomal embedding reshapes the dynamics of abasic sites

Apurinic/apyrimidinic (AP) sites are the most common DNA lesions, which benefit from a most efficient repair by the base excision pathway. The impact of losing a nucleobase on the conformation and dynamics of B-DNA is well characterized. Yet AP sites seem to present an entirely different chemistry i...

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Detalles Bibliográficos
Autores principales: Bignon, Emmanuelle, Claerbout, Victor E. P., Jiang, Tao, Morell, Christophe, Gillet, Natacha, Dumont, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560594/
https://www.ncbi.nlm.nih.gov/pubmed/33057206
http://dx.doi.org/10.1038/s41598-020-73997-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560594/
https://www.ncbi.nlm.nih.gov/pubmed/33057206
http://dx.doi.org/10.1038/s41598-020-73997-y

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