An enhanced genetic model of relapsed IGH-translocated multiple myeloma evolutionary dynamics

Most patients with multiple myeloma (MM) die from progressive disease after relapse. To advance our understanding of MM evolution mechanisms, we performed whole-genome sequencing of 80 IGH-translocated tumour-normal newly diagnosed pairs and 24 matched relapsed tumours from the Myeloma XI trial. We...

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Detalles Bibliográficos
Autores principales: Hoang, Phuc H., Cornish, Alex J., Sherborne, Amy L., Chubb, Daniel, Kimber, Scott, Jackson, Graham, Morgan, Gareth J., Cook, Gordon, Kinnersley, Ben, Kaiser, Martin, Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560599/
https://www.ncbi.nlm.nih.gov/pubmed/33057009
http://dx.doi.org/10.1038/s41408-020-00367-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560599/
https://www.ncbi.nlm.nih.gov/pubmed/33057009
http://dx.doi.org/10.1038/s41408-020-00367-2

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