A genotyping method combining primer competition PCR with HRM analysis to identify point mutations in Duchenne animal models

Dystrophin-null sapje zebrafish is an excellent model for better understanding the pathological mechanisms underlying Duchenne muscular dystrophy, and it has recently arisen as a powerful tool for high-throughput screening of therapeutic candidates for this disease. While dystrophic phenotype in sap...

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Detalles Bibliográficos
Autores principales: Lasa-Fernandez, Haizpea, Mosqueira-Martín, Laura, Alzualde, Ainhoa, Lasa-Elgarresta, Jaione, Vallejo-Illarramendi, Ainara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560699/
https://www.ncbi.nlm.nih.gov/pubmed/33057138
http://dx.doi.org/10.1038/s41598-020-74173-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560699/
https://www.ncbi.nlm.nih.gov/pubmed/33057138
http://dx.doi.org/10.1038/s41598-020-74173-y

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