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A genotyping method combining primer competition PCR with HRM analysis to identify point mutations in Duchenne animal models
Dystrophin-null sapje zebrafish is an excellent model for better understanding the pathological mechanisms underlying Duchenne muscular dystrophy, and it has recently arisen as a powerful tool for high-throughput screening of therapeutic candidates for this disease. While dystrophic phenotype in sap...
Autores principales: | Lasa-Fernandez, Haizpea, Mosqueira-Martín, Laura, Alzualde, Ainhoa, Lasa-Elgarresta, Jaione, Vallejo-Illarramendi, Ainara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560699/ https://www.ncbi.nlm.nih.gov/pubmed/33057138 http://dx.doi.org/10.1038/s41598-020-74173-y |
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