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Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23
Multiple Myeloma (MM) induces bone destruction, decreases bone formation, and increases marrow angiogenesis in patients. We reported that osteocytes (Ocys) directly interact with MM cells to increase tumor growth and expression of Ocy-derived factors that promote bone resorption and suppress bone fo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560700/ https://www.ncbi.nlm.nih.gov/pubmed/33057033 http://dx.doi.org/10.1038/s41598-020-74352-x |