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Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23

Multiple Myeloma (MM) induces bone destruction, decreases bone formation, and increases marrow angiogenesis in patients. We reported that osteocytes (Ocys) directly interact with MM cells to increase tumor growth and expression of Ocy-derived factors that promote bone resorption and suppress bone fo...

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Detalles Bibliográficos
Autores principales: Mulcrone, Patrick L., Edwards, Shanique K. E., Petrusca, Daniela N., Haneline, Laura S., Delgado-Calle, Jesús, Roodman, G. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560700/
https://www.ncbi.nlm.nih.gov/pubmed/33057033
http://dx.doi.org/10.1038/s41598-020-74352-x