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Design and in vivo evaluation of a microparticulate depot formulation of buprenorphine for veterinary use

Buprenorphine is a frequently used analgetic agent in veterinary medicine. A major drawback, however, is the short duration of action requiring several daily administrations. We therefore designed a poly-lactic-co-glycolic acid (PLGA) based microparticulate drug formulation for sustained parenteral...

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Detalles Bibliográficos
Autores principales: Schreiner, Viktoria, Durst, Mattea, Arras, Margarete, Detampel, Pascal, Jirkof, Paulin, Huwyler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560740/
https://www.ncbi.nlm.nih.gov/pubmed/33057103
http://dx.doi.org/10.1038/s41598-020-74230-6