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Design and in vivo evaluation of a microparticulate depot formulation of buprenorphine for veterinary use
Buprenorphine is a frequently used analgetic agent in veterinary medicine. A major drawback, however, is the short duration of action requiring several daily administrations. We therefore designed a poly-lactic-co-glycolic acid (PLGA) based microparticulate drug formulation for sustained parenteral...
Autores principales: | Schreiner, Viktoria, Durst, Mattea, Arras, Margarete, Detampel, Pascal, Jirkof, Paulin, Huwyler, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560740/ https://www.ncbi.nlm.nih.gov/pubmed/33057103 http://dx.doi.org/10.1038/s41598-020-74230-6 |
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