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Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment

Poor viability of mesenchymal stem cells (MSCs) at the transplanted site often hinders the efficacy of MSCs-based therapy. Platelet lysate (PL) contains rich amounts of growth factors, which benefits cell growth. This study aimed to explore how human PL benefits umbilical cord-derived MSCs (huc-MSCs...

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Detalles Bibliográficos
Autores principales: Yan, Li, Zhou, Li, Yan, Bo, Zhang, Lei, Du, Wenxi, Liu, Fucun, Yuan, Qiang, Tong, Peijian, Shan, Letian, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560841/
https://www.ncbi.nlm.nih.gov/pubmed/33057008
http://dx.doi.org/10.1038/s41419-020-03045-0