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Dermal fibroblasts have different extracellular matrix profiles induced by TGF-β, PDGF and IL-6 in a model for skin fibrosis

Different stimulants might induce different extracellular matrix profiles. It is essential to gain an understanding and quantification of these changes to allow for focused anti-fibrotic drug development. This study investigated the expression of extracellular matrix by dermal fibroblast mimicking f...

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Detalles Bibliográficos
Autores principales: Juhl, Pernille, Bondesen, Sandie, Hawkins, Clare Louise, Karsdal, Morten Asser, Bay-Jensen, Anne-Christine, Davies, Michael Jonathan, Siebuhr, Anne Sofie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560847/
https://www.ncbi.nlm.nih.gov/pubmed/33057073
http://dx.doi.org/10.1038/s41598-020-74179-6