Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1

Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, has greatly affected clinical outcomes in non-small cell lung cancer (NSCLC) patients. The long noncoding RNAs (lncRNAs) are known to regulate tumorigenesis and cancer progression, but their con...

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Detalles Bibliográficos
Autores principales: Chen, Zhenyao, Chen, Qinnan, Cheng, Zhixiang, Gu, Jingyao, Feng, Wenyan, Lei, Tianyao, Huang, Jiali, Pu, Jiaze, Chen, Xin, Wang, Zhaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560854/
https://www.ncbi.nlm.nih.gov/pubmed/33056982
http://dx.doi.org/10.1038/s41419-020-03047-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560854/
https://www.ncbi.nlm.nih.gov/pubmed/33056982
http://dx.doi.org/10.1038/s41419-020-03047-y

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