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Elevated perfusate [Na(+)] increases contractile dysfunction during ischemia and reperfusion

Recent studies revealed that relatively small changes in perfusate sodium ([Na(+)](o)) composition significantly affect cardiac electrical conduction and stability in contraction arrested ex vivo Langendorff heart preparations before and during simulated ischemia. Additionally, [Na(+)](o) modulates...

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Detalles Bibliográficos
Autores principales: King, D. Ryan, Padget, Rachel L., Perry, Justin, Hoeker, Gregory, Smyth, James W., Brown, David A., Poelzing, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560862/
https://www.ncbi.nlm.nih.gov/pubmed/33057157
http://dx.doi.org/10.1038/s41598-020-74069-x