Cargando…
Elevated perfusate [Na(+)] increases contractile dysfunction during ischemia and reperfusion
Recent studies revealed that relatively small changes in perfusate sodium ([Na(+)](o)) composition significantly affect cardiac electrical conduction and stability in contraction arrested ex vivo Langendorff heart preparations before and during simulated ischemia. Additionally, [Na(+)](o) modulates...
Autores principales: | King, D. Ryan, Padget, Rachel L., Perry, Justin, Hoeker, Gregory, Smyth, James W., Brown, David A., Poelzing, Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560862/ https://www.ncbi.nlm.nih.gov/pubmed/33057157 http://dx.doi.org/10.1038/s41598-020-74069-x |
Ejemplares similares
-
Reevaluating methods reporting practices to improve reproducibility: an analysis of methodological rigor for the Langendorff whole heart technique
por: King, D. Ryan, et al.
Publicado: (2022) -
Electrophysiologic effects of the I(K)
(1) inhibitor PA‐6 are modulated by extracellular potassium in isolated guinea pig hearts
por: Hoeker, Gregory S., et al.
Publicado: (2017) -
The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium
por: King, D. Ryan, et al.
Publicado: (2021) -
Sex Differences in β-Adrenergic Responsiveness of Action Potentials and Intracellular Calcium Handling in Isolated Rabbit Hearts
por: Hoeker, Gregory S., et al.
Publicado: (2014) -
Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study
por: Veeraraghavan, Rengasayee, et al.
Publicado: (2015)