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Mathematical model predicts response to chemotherapy in advanced non-resectable non-small cell lung cancer patients treated with platinum-based doublet

We developed a computational platform including machine learning and a mechanistic mathematical model to find the optimal protocol for administration of platinum-doublet chemotherapy in a palliative setting. The platform has been applied to advanced metastatic non-small cell lung cancer (NSCLC). The...

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Detalles Bibliográficos
Autores principales: Kozłowska, Emilia, Suwiński, Rafał, Giglok, Monika, Świerniak, Andrzej, Kimmel, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561182/
https://www.ncbi.nlm.nih.gov/pubmed/33017420
http://dx.doi.org/10.1371/journal.pcbi.1008234