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Mathematical model predicts response to chemotherapy in advanced non-resectable non-small cell lung cancer patients treated with platinum-based doublet
We developed a computational platform including machine learning and a mechanistic mathematical model to find the optimal protocol for administration of platinum-doublet chemotherapy in a palliative setting. The platform has been applied to advanced metastatic non-small cell lung cancer (NSCLC). The...
Autores principales: | Kozłowska, Emilia, Suwiński, Rafał, Giglok, Monika, Świerniak, Andrzej, Kimmel, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561182/ https://www.ncbi.nlm.nih.gov/pubmed/33017420 http://dx.doi.org/10.1371/journal.pcbi.1008234 |
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