Characterization of hepatic macrophages and evaluation of inflammatory response in heme oxygenase-1 deficient mice exposed to scAAV9 vectors

Adeno-associated viral (AAV) vectors are characterised by low immunogenicity, although humoral and cellular responses may be triggered upon infection. Following systemic administration high levels of vector particles accumulate within the liver. Kupffer cells (KCs) are liver resident macrophages and...

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Detalles Bibliográficos
Autores principales: Tomczyk, Mateusz, Kraszewska, Izabela, Mąka, Robert, Waligórska, Agnieszka, Dulak, Józef, Jaźwa-Kusior, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561190/
https://www.ncbi.nlm.nih.gov/pubmed/33057437
http://dx.doi.org/10.1371/journal.pone.0240691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561190/
https://www.ncbi.nlm.nih.gov/pubmed/33057437
http://dx.doi.org/10.1371/journal.pone.0240691

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