Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen

Truncating mutations in the tumour suppressor gene APC occur frequently in colorectal cancers and result in the deregulation of Wnt signalling as well as changes in cell-cell adhesion. Using quantitative imaging based on the detection of membrane-associated E-cadherin, we undertook a protein coding...

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Detalles Bibliográficos
Autores principales: King, Lauren E., Zhang, Hui-Hua, Gould, Cathryn M., Thomas, Daniel W., Whitehead, Lachlan W., Simpson, Kaylene J., Burgess, Antony W., Faux, Maree C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561197/
https://www.ncbi.nlm.nih.gov/pubmed/33057364
http://dx.doi.org/10.1371/journal.pone.0240746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561197/
https://www.ncbi.nlm.nih.gov/pubmed/33057364
http://dx.doi.org/10.1371/journal.pone.0240746

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