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Continuous Exposure of Breast Cancer Cells to Tamoxifen Upregulates GPER-1 and Increases Cell Proliferation

GPER-1 is a novel membrane sited G protein-coupled estrogen receptor. Clinical studies have shown that patients suffering an estrogen receptor α (ERα)/GPER-1 positive, breast cancer have a lower survival rate than those who have developed ERα-positive/GPER-1 negative tumors. Moreover, absence of GPE...

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Detalles Bibliográficos
Autores principales: Molina, Luis, Bustamante, Felipe, Ortloff, Alexander, Ramos, Iraidi, Ehrenfeld, Pamela, Figueroa, Carlos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561417/
https://www.ncbi.nlm.nih.gov/pubmed/33117280
http://dx.doi.org/10.3389/fendo.2020.563165