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Damaged Myofiber-Derived Metabolic Enzymes Act as Activators of Muscle Satellite Cells

Muscle satellite cells are normally quiescent but are rapidly activated following muscle damage. Here, we investigated whether damaged myofibers influence the activation of satellite cells. Our findings revealed that satellite cells are directly activated by damaged-myofiber-derived factors (DMDFs)....

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Detalles Bibliográficos
Autores principales: Tsuchiya, Yoshifumi, Kitajima, Yasuo, Masumoto, Hiroshi, Ono, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561495/
https://www.ncbi.nlm.nih.gov/pubmed/32888505
http://dx.doi.org/10.1016/j.stemcr.2020.08.002