Vast Self-Renewal Potential of Human AGM Region HSCs Dramatically Declines in the Umbilical Cord Blood

Human hematopoietic stem cells (HSCs) emerge in the aorta-gonad-mesonephros (AGM) region during Carnegie stages (CS) 14–17. Although we previously reported that these HSCs can generate no less than 300 daughter HSCs, their actual number has never been established. Here, we show that a single human A...

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Detalles Bibliográficos
Autores principales: Ivanovs, Andrejs, Rybtsov, Stanislav, Anderson, Richard A., Medvinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561509/
https://www.ncbi.nlm.nih.gov/pubmed/32946804
http://dx.doi.org/10.1016/j.stemcr.2020.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561509/
https://www.ncbi.nlm.nih.gov/pubmed/32946804
http://dx.doi.org/10.1016/j.stemcr.2020.08.008

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