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Centrosome Reduction Promotes Terminal Differentiation of Human Cardiomyocytes

Centrosome reduction and redistribution of pericentriolar material (PCM) coincides with cardiomyocyte transitions to a post-mitotic and matured state. However, it is unclear whether centrosome changes are a cause or consequence of terminal differentiation. We validated that centrosomes were intact a...

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Detalles Bibliográficos
Autores principales: Ng, Dominic C.H., Richards, Dominic K., Mills, Richard J., Ho, Uda Y., Perks, Hannah L., Tucker, Callum R., Voges, Holly K., Pagan, Julia K., Hudson, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561510/
https://www.ncbi.nlm.nih.gov/pubmed/32946803
http://dx.doi.org/10.1016/j.stemcr.2020.08.007