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An In Vitro Partial Lesion Model of Differentiated Human Mesencephalic Neurons: Effect of Pericyte Secretome on Phenotypic Markers

Parkinson’s disease (PD) is characterised by the progressive degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta. Post-mortem data suggests that the loss of DA markers may long precede the cell death, leaving a window to rescue the DA phenotype. Screening for potential ne...

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Detalles Bibliográficos
Autores principales: Gaceb, Abderahim, Barbariga, Marco, Paul, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561585/
https://www.ncbi.nlm.nih.gov/pubmed/32472394
http://dx.doi.org/10.1007/s12031-020-01589-6