mTORC1 hyperactivation in lymphangioleiomyomatosis leads to ACE2 upregulation in type II pneumocytes: implications for COVID-19

Increased pneumocyte expression of the SARS-CoV-2 entry receptor ACE2 in lymphangioleiomyomatosis (LAM) is associated with upregulation of interferon pathways in natural killer cells as well as increased IL6 expression in LAM-associated fibroblasts https://bit.ly/34ChSsg

Detalles Bibliográficos
Autores principales: Tang, Yan, Kwiatkowski, David J., Henske, Elizabeth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Agora
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562695/
https://www.ncbi.nlm.nih.gov/pubmed/33060154
http://dx.doi.org/10.1183/13993003.02737-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562695/
https://www.ncbi.nlm.nih.gov/pubmed/33060154
http://dx.doi.org/10.1183/13993003.02737-2020

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