Cargando…
Distribution of disease-causing germline mutations in coiled-coils implies an important role of their N-terminal region
Next-generation sequencing resulted in the identification of a huge number of naturally occurring variations in human proteins. The correct interpretation of the functional effects of these variations necessitates the understanding of how they modulate protein structure. Coiled-coils are α-helical s...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562717/ https://www.ncbi.nlm.nih.gov/pubmed/33060664 http://dx.doi.org/10.1038/s41598-020-74354-9 |