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Genome targeting by hybrid Flp-TAL recombinases

Genome engineering is a rapidly evolving field that benefits from the availability of different tools that can be used to perform genome manipulation tasks. We describe here the development of the Flp-TAL recombinases that can target genomic FRT-like sequences in their native chromosomal locations....

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Detalles Bibliográficos
Autores principales: Voziyanova, Eugenia, Li, Feng, Shah, Riddhi, Voziyanov, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562724/
https://www.ncbi.nlm.nih.gov/pubmed/33060660
http://dx.doi.org/10.1038/s41598-020-74474-2