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Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects

During mouse embryonic development, vasculogenesis initially occurs in the yolk sac, preceding neurulation. Our previous studies have demonstrated that maternal diabetes induces embryonic vasculopathy at early embryonic developmental stage by suppressing the expression of vascular growth factors inc...

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Detalles Bibliográficos
Autores principales: Cao, Songying, Reece, E. Albert, Shen, Wei-Bin, Yang, Peixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562732/
https://www.ncbi.nlm.nih.gov/pubmed/33060561
http://dx.doi.org/10.1038/s41419-020-03078-5