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Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa

BACKGROUND: CpG methylation of tumor suppressor genes occurs in the early stage of carcinogenesis. Detecting risk factors for aberrant CpG methylation is clinically important for predicting cancer development. DNA methyltransferase (DNMT) 3a is considered to play critical roles in the DNA methylatio...

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Detalles Bibliográficos
Autores principales: Takano, Hikaru, Shibata, Tomoyuki, Nakamura, Masakatsu, Sakurai, Naoko, Hayashi, Tasuku, Ota, Masafumi, Nomura-Horita, Tomoe, Hayashi, Ranji, Shimasaki, Takeo, Otsuka, Toshimi, Tahara, Tomomitsu, Arisawa, Tomiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562764/
https://www.ncbi.nlm.nih.gov/pubmed/33066747
http://dx.doi.org/10.1186/s12881-020-01142-7