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Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa
BACKGROUND: CpG methylation of tumor suppressor genes occurs in the early stage of carcinogenesis. Detecting risk factors for aberrant CpG methylation is clinically important for predicting cancer development. DNA methyltransferase (DNMT) 3a is considered to play critical roles in the DNA methylatio...
Autores principales: | Takano, Hikaru, Shibata, Tomoyuki, Nakamura, Masakatsu, Sakurai, Naoko, Hayashi, Tasuku, Ota, Masafumi, Nomura-Horita, Tomoe, Hayashi, Ranji, Shimasaki, Takeo, Otsuka, Toshimi, Tahara, Tomomitsu, Arisawa, Tomiyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562764/ https://www.ncbi.nlm.nih.gov/pubmed/33066747 http://dx.doi.org/10.1186/s12881-020-01142-7 |
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