The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics

The human cathelicidin LL-37 serves a critical role in the innate immune system defending bacterial infections. LL-37 can interact with molecules of the cell wall and perforate cytoplasmic membranes resulting in bacterial cell death. To test the interactions of LL-37 and bacterial cell wall componen...

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Detalles Bibliográficos
Autores principales: Sancho-Vaello, Enea, Gil-Carton, David, François, Patrice, Bonetti, Eve-Julie, Kreir, Mohamed, Pothula, Karunakar Reddy, Kleinekathöfer, Ulrich, Zeth, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562864/
https://www.ncbi.nlm.nih.gov/pubmed/33060695
http://dx.doi.org/10.1038/s41598-020-74401-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562864/
https://www.ncbi.nlm.nih.gov/pubmed/33060695
http://dx.doi.org/10.1038/s41598-020-74401-5

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