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Duodenal acidification induces gastric relaxation and alters epithelial barrier function by a mast cell independent mechanism

Duodenal hyperpermeability and low-grade inflammation in functional dyspepsia is potentially related to duodenal acid exposure. We aimed to evaluate in healthy volunteers the involvement of mast cell activation on the duodenogastric reflex and epithelial integrity during duodenal acidification. This...

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Detalles Bibliográficos
Autores principales: Vanheel, Hanne, Vicario, Maria, Beeckmans, Dorien, Cocca, Silvia, Wauters, Lucas, Accarie, Alison, Toth, Joran, Rodewald, Hans-Reimer, De Hertogh, Gert, Matteoli, Gianluca, Boeckxstaens, Guy, Tack, Jan, Farre, Ricard, Vanuytsel, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562901/
https://www.ncbi.nlm.nih.gov/pubmed/33060783
http://dx.doi.org/10.1038/s41598-020-74491-1