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Duodenal acidification induces gastric relaxation and alters epithelial barrier function by a mast cell independent mechanism
Duodenal hyperpermeability and low-grade inflammation in functional dyspepsia is potentially related to duodenal acid exposure. We aimed to evaluate in healthy volunteers the involvement of mast cell activation on the duodenogastric reflex and epithelial integrity during duodenal acidification. This...
Autores principales: | Vanheel, Hanne, Vicario, Maria, Beeckmans, Dorien, Cocca, Silvia, Wauters, Lucas, Accarie, Alison, Toth, Joran, Rodewald, Hans-Reimer, De Hertogh, Gert, Matteoli, Gianluca, Boeckxstaens, Guy, Tack, Jan, Farre, Ricard, Vanuytsel, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562901/ https://www.ncbi.nlm.nih.gov/pubmed/33060783 http://dx.doi.org/10.1038/s41598-020-74491-1 |
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