Theoretical study of the impact of adaptation on cell-fate heterogeneity and fractional killing

Fractional killing illustrates the cell propensity to display a heterogeneous fate response over a wide range of stimuli. The interplay between the nonlinear and stochastic dynamics of biochemical networks plays a fundamental role in shaping this probabilistic response and in reconciling requirement...

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Detalles Bibliográficos
Autores principales: Hurbain, Julien, Labavić, Darka, Thommen, Quentin, Pfeuty, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562916/
https://www.ncbi.nlm.nih.gov/pubmed/33060729
http://dx.doi.org/10.1038/s41598-020-74238-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562916/
https://www.ncbi.nlm.nih.gov/pubmed/33060729
http://dx.doi.org/10.1038/s41598-020-74238-y

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