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Theoretical study of the impact of adaptation on cell-fate heterogeneity and fractional killing
Fractional killing illustrates the cell propensity to display a heterogeneous fate response over a wide range of stimuli. The interplay between the nonlinear and stochastic dynamics of biochemical networks plays a fundamental role in shaping this probabilistic response and in reconciling requirement...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562916/ https://www.ncbi.nlm.nih.gov/pubmed/33060729 http://dx.doi.org/10.1038/s41598-020-74238-y |