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Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

Human glial progenitor cells (hGPCs) are promising cellular substrates to explore for the in situ production of new neurons for brain repair. Proof of concept for direct neuronal reprogramming of glial progenitors has been obtained in mouse models in vivo, but conversion using human cells has not ye...

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Detalles Bibliográficos
Autores principales: Nolbrant, Sara, Giacomoni, Jessica, Hoban, Deirdre B., Bruzelius, Andreas, Birtele, Marcella, Chandler-Militello, Devin, Pereira, Maria, Ottosson, Daniella Rylander, Goldman, Steven A., Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562948/
https://www.ncbi.nlm.nih.gov/pubmed/32976765
http://dx.doi.org/10.1016/j.stemcr.2020.08.013