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Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons
Human glial progenitor cells (hGPCs) are promising cellular substrates to explore for the in situ production of new neurons for brain repair. Proof of concept for direct neuronal reprogramming of glial progenitors has been obtained in mouse models in vivo, but conversion using human cells has not ye...
Autores principales: | Nolbrant, Sara, Giacomoni, Jessica, Hoban, Deirdre B., Bruzelius, Andreas, Birtele, Marcella, Chandler-Militello, Devin, Pereira, Maria, Ottosson, Daniella Rylander, Goldman, Steven A., Parmar, Malin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562948/ https://www.ncbi.nlm.nih.gov/pubmed/32976765 http://dx.doi.org/10.1016/j.stemcr.2020.08.013 |
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