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Synthetic Notch-Receptor-Mediated Transmission of a Transient Signal into Permanent Information via CRISPR/Cas9-Based Genome Editing

Synthetic receptor biology and genome editing are emerging techniques, both of which are currently beginning to be used in preclinical and clinical applications. We were interested in whether a combination of these techniques approaches would allow for the generation of a novel type of reporter cell...

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Detalles Bibliográficos
Autores principales: Sgodda, Malte, Alfken, Susanne, Schambach, Axel, Eggenschwiler, Reto, Fidzinski, Pawel, Hummel, Michael, Cantz, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563181/
https://www.ncbi.nlm.nih.gov/pubmed/32825374
http://dx.doi.org/10.3390/cells9091929