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Recognition of Dimeric Lewis X by Anti-Dimeric Le(x) Antibody SH2

The carbohydrate antigen dimeric Lewis X (DimLe(x)), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics. Using the native DimLe(x) antigen as a vaccine would elicit an autoimmune response against the Le(x) antigen found on normal, healthy...

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Detalles Bibliográficos
Autores principales: Jegatheeswaran, Sinthuja, Asnani, Ari, Forman, Adam, Hendel, Jenifer L., Moore, Christopher J., Nejatie, Ali, Wang, An, Wang, Jo-Wen, Auzanneau, France-Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563222/
https://www.ncbi.nlm.nih.gov/pubmed/32957489
http://dx.doi.org/10.3390/vaccines8030538