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Recognition of Dimeric Lewis X by Anti-Dimeric Le(x) Antibody SH2
The carbohydrate antigen dimeric Lewis X (DimLe(x)), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics. Using the native DimLe(x) antigen as a vaccine would elicit an autoimmune response against the Le(x) antigen found on normal, healthy...
Autores principales: | Jegatheeswaran, Sinthuja, Asnani, Ari, Forman, Adam, Hendel, Jenifer L., Moore, Christopher J., Nejatie, Ali, Wang, An, Wang, Jo-Wen, Auzanneau, France-Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563222/ https://www.ncbi.nlm.nih.gov/pubmed/32957489 http://dx.doi.org/10.3390/vaccines8030538 |
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