A Fluorescent Assay to Search for Inhibitors of HIV-1 Integrase Interactions with Human Ku70 Protein, and Its Application for Characterization of Oligonucleotide Inhibitors

The search for compounds that can inhibit the interaction of certain viral proteins with their cellular partners is a promising trend in the development of antiviral drugs. We have previously shown that binding of HIV-1 integrase with human Ku70 protein is essential for viral replication. Here, we p...

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Detalles Bibliográficos
Autores principales: Galkin, Simon, Rozina, Anna, Zalevsky, Arthur, Gottikh, Marina, Anisenko, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563236/
https://www.ncbi.nlm.nih.gov/pubmed/32854330
http://dx.doi.org/10.3390/biom10091236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563236/
https://www.ncbi.nlm.nih.gov/pubmed/32854330
http://dx.doi.org/10.3390/biom10091236

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