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Cancer-Specific Immune Prognostic Signature in Solid Tumors and Its Relation to Immune Checkpoint Therapies

To elucidate the role of immune cell infiltration as a prognostic signature in solid tumors, we analyzed immune-function-related genes from four publicly available single-cell RNA-Seq data sets and twenty bulk tumor RNA-Seq data sets from The Cancer Genome Atlas (TCGA). Unsupervised clustering of pa...

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Detalles Bibliográficos
Autores principales: Das, Shaoli, Camphausen, Kevin, Shankavaram, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563367/
https://www.ncbi.nlm.nih.gov/pubmed/32882873
http://dx.doi.org/10.3390/cancers12092476