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Origin of Genome Instability and Determinants of Mutational Landscape in Cancer Cells
Genome instability is a crucial and early event associated with an increased predisposition to tumor formation. In the absence of any exogenous agent, a single human cell is subjected to about 70,000 DNA lesions each day. It has now been shown that physiological cellular processes including DNA tran...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563369/ https://www.ncbi.nlm.nih.gov/pubmed/32967144 http://dx.doi.org/10.3390/genes11091101 |