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Selective Targeting of the Hedgehog Signaling Pathway by PBM Nanoparticles in Docetaxel-Resistant Prostate Cancer

An abnormality in hedgehog (Hh) signaling has been implicated in the progression of prostate cancer (PCa) to a more aggressive and therapy-resistant disease. Our assessments of human PCa tissues have shown an overexpression of the Hh pathway molecules, glioma-associated oncogene homolog 1 (GLI-1), a...

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Detalles Bibliográficos
Autores principales: Singh, Santosh Kumar, Gordetsky, Jennifer B., Bae, Sejong, Acosta, Edward P., Lillard, James W., Singh, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563377/
https://www.ncbi.nlm.nih.gov/pubmed/32867229
http://dx.doi.org/10.3390/cells9091976