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Aberrant Methylation of LINE-1 Transposable Elements: A Search for Cancer Biomarkers

Cancer remains one of the main causes of human mortality despite significant progress in its diagnostics and therapy achieved in the past decade. Massive hypomethylation of retrotransposons, in particular LINE-1, is considered a hallmark of most malignant transformations as it results in the reactiv...

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Detalles Bibliográficos
Autores principales: Ponomaryova, Anastasia A., Rykova, Elena Y., Gervas, Polina A., Cherdyntseva, Nadezhda V., Mamedov, Ilgar Z., Azhikina, Tatyana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563416/
https://www.ncbi.nlm.nih.gov/pubmed/32887319
http://dx.doi.org/10.3390/cells9092017