Bioinformatics Data Mining Repurposes the JAK2 (Janus Kinase 2) Inhibitor Fedratinib for Treating Pancreatic Ductal Adenocarcinoma by Reversing the KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog)-Driven Gene Signature

Pancreatic ductal adenocarcinoma (PDAC) is still one of the most aggressive and lethal cancer types due to the late diagnosis, high metastatic potential, and drug resistance. The development of novel therapeutic strategies is urgently needed. KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) is th...

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Detalles Bibliográficos
Autores principales: Liu, Li-Wei, Hsieh, Yao-Yu, Yang, Pei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563462/
https://www.ncbi.nlm.nih.gov/pubmed/32947833
http://dx.doi.org/10.3390/jpm10030130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563462/
https://www.ncbi.nlm.nih.gov/pubmed/32947833
http://dx.doi.org/10.3390/jpm10030130

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