Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain

Single-minded homologue 1 (SIM1) is a transcription factor with numerous different physiological and developmental functions. SIM1 is a member of the class I basic helix-loop-helix-PER-ARNT-SIM (bHLH–PAS) transcription factor family, that includes several other conserved proteins, including the hypo...

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Detalles Bibliográficos
Autores principales: Coban, Mathew A., Blackburn, Patrick R., Whitelaw, Murray L., van Haelst, Mieke M., Atwal, Paldeep S., Caulfield, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563489/
https://www.ncbi.nlm.nih.gov/pubmed/32932609
http://dx.doi.org/10.3390/biom10091314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563489/
https://www.ncbi.nlm.nih.gov/pubmed/32932609
http://dx.doi.org/10.3390/biom10091314

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