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Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

Murine models of cytomegalovirus (CMV) infection have revealed an exceptional kinetics of the immune response. After resolution of productive infection, transient contraction of the viral epitope-specific CD8 T-cell pool was found to be followed by a pool expansion specific for certain viral epitope...

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Detalles Bibliográficos
Autores principales: Holtappels, Rafaela, Freitag, Kirsten, Renzaho, Angelique, Becker, Sara, Lemmermann, Niels A.W., Reddehase, Matthias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563500/
https://www.ncbi.nlm.nih.gov/pubmed/32707744
http://dx.doi.org/10.3390/vaccines8030402