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Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors
Murine models of cytomegalovirus (CMV) infection have revealed an exceptional kinetics of the immune response. After resolution of productive infection, transient contraction of the viral epitope-specific CD8 T-cell pool was found to be followed by a pool expansion specific for certain viral epitope...
Autores principales: | Holtappels, Rafaela, Freitag, Kirsten, Renzaho, Angelique, Becker, Sara, Lemmermann, Niels A.W., Reddehase, Matthias J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563500/ https://www.ncbi.nlm.nih.gov/pubmed/32707744 http://dx.doi.org/10.3390/vaccines8030402 |
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