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Solid Lipid Nanoparticle Carrier Platform Containing Synthetic TLR4 Agonist Mediates Non-Viral DNA Vaccine Delivery

There is a growing demand for better delivery systems to improve the stability and efficacy of DNA vaccines. Here we report the synthesis of a non-viral DNA vaccine delivery system using a novel adjuvanted solid lipid nanoparticle (SLN-A) platform as a carrier for a DNA vaccine candidate encoding th...

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Detalles Bibliográficos
Autores principales: Francis, Jasmine E., Skakic, Ivana, Dekiwadia, Chaitali, Shukla, Ravi, Taki, Aya C., Walduck, Anna, Smooker, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563538/
https://www.ncbi.nlm.nih.gov/pubmed/32967285
http://dx.doi.org/10.3390/vaccines8030551