Akt+ IKKα/β+ Rab5+ Signalosome Mediate the Endosomal Recruitment of Sec61 and Contribute to Cross-Presentation in Bone Marrow Precursor Cells

Cross-presentation in dendritic cells (DC) requires the endosomal relocations of internalized antigens and the endoplasmic reticulum protein Sec61. Despite the fact that endotoxin-containing pathogen and endotoxin-free antigen have different effects on protein kinase B (Akt) and I-kappa B Kinase α/β...

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Detalles Bibliográficos
Autores principales: Xu, Dan Dan, Hu, Chun Fang, You, Xiang, Lu, Nan Nan, Gao, Feng Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563657/
https://www.ncbi.nlm.nih.gov/pubmed/32957586
http://dx.doi.org/10.3390/vaccines8030539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563657/
https://www.ncbi.nlm.nih.gov/pubmed/32957586
http://dx.doi.org/10.3390/vaccines8030539

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