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Artemisinin Derivatives Stimulate DR5-Specific TRAIL-Induced Apoptosis by Regulating Wildtype P53

SIMPLE SUMMARY: The risk of developing colorectal cancer at a younger age has increased, but current therapies are either risky or limited. We aim to demonstrate that the combination treatment of artemisinin derivatives and TRAIL could be a potential therapy to kill colon cancer cells. We found that...

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Detalles Bibliográficos
Autores principales: Zhou, Xinyu, Zijlstra, Sietske N., Soto-Gamez, Abel, Setroikromo, Rita, Quax, Wim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563660/
https://www.ncbi.nlm.nih.gov/pubmed/32899699
http://dx.doi.org/10.3390/cancers12092514