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Impact of Pre-Existing Immunity on Live Attenuated Influenza Vaccine-Induced Cross-Protective Immunity

The efficacy of the intranasally (i.n.) delivered live attenuated influenza vaccine (LAIV) is variable and, in some seasons, suboptimal. In this study, we report that LAIV exhibits cross-protective efficacy in mice, potentially associated with cellular immunity as opposed to antigen-specific antibod...

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Detalles Bibliográficos
Autores principales: Roy, Sreeja, Williams, Clare M, Pardo, Julian, Wijesundara, Danushka K, Furuya, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563680/
https://www.ncbi.nlm.nih.gov/pubmed/32825218
http://dx.doi.org/10.3390/vaccines8030459